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Make any changes necessary for Inbound layouts.
Save when done.
Assign User Profiles to a Softphone Layout Assignment
Note: You must have added at least one user to the Call Centre before you can create any Softphone Layout Assignments.
The assignment controls which layout a group (profile) of users is associated with and therefore what screens are popped when they answer a call.
Navigate to the Salesforce Setup menu
Search for 'Softphone Layouts'.
Click 'Softphone Layout Assignment'
Choose the User Profile that you want to assign the layout to.
Chose the Layout you want to associate wit the selected User Profile.
Click Save.